By Eiko I. Fried and Michiel van Elk
Much optimism has been expressed about the potential of psychedelics to treat mental health problems such as suicidal ideation, depression, and post-traumatic stress disorder. This optimism goes hand in hand with a notable increase in research publications, investments from pharmaceutical companies, patent filings, media exposure, as well as shifts in political and legislative landscapes. In the U.S., hundreds of ketamine clinics have emerged in the last years, and Australia just recently acknowledged psychedelics as medicines.
In our new paper in print in the journal Therapeutic Advances in Psychopharmacology, titled “History repeating: Guidelines to address common problems in psychedelic science,” we critically discuss whether this optimism is warranted, given current empirical work. One of us (Dr. Eiko Fried) is an Associate Professor in Clinical Psychology who studies and teaches conducting and evaluating clinical trials for mental health problems such as depression, with a focus on the question what valid inferences can be drawn from empirical data. The other (Dr. Michiel van Elk) is an Associate Professor in Cognitive Psychology, with a long-standing interest in the topic of altered states of consciousness (including, but not limited to, states induced through psychedelics), who, together with the PRSM lab, uses a multi-method research approach, open science practices and replication studies to study these experiences in the lab and in naturalistic settings.